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Why are generic pills cheaper than the brand name ones?

The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability.
Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs.
First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions.
Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug.
Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.

Generic LasixDiuretics / Generic Lasix
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Furosemide is used for:

Treating fluid build-up and swelling caused by congestive heart failure, liver cirrhosis, or kidney disease. It is also used in combination with other medicines to treat fluid build-up in the lungs. It may also be used for other conditions as determined by your doctor.

Furosemide is a loop diuretic. Loop diuretics make the kidneys eliminate larger amounts of electrolytes (especially sodium and potassium salts) and water than normal (diuretic effect). Loop diuretics are useful for treating many conditions in which salt and water retention (eg, edema, swelling) is a problem.

Do NOT use Furosemide if:

  • you are allergic to any ingredient in Furosemide or to sulfonamides
  • you are unable to urinate

Contact your doctor or health care provider right away if any of these apply to you.

Before using Furosemide :

Some medical conditions may interact with Furosemide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, plan to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have fluid in your abdomen, hearing impairment, liver disease, diabetes mellitus, low urine output, high blood uric acid levels, a blood disorder, kidney disease, lupus, have had a heart attack, or are dehydrated

Some MEDICINES MAY INTERACT with Furosemide. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin) because they may decrease the effectiveness of Furosemide
  • Angiotensin-converting enzyme (ACE) inhibitors (eg, captopril), aminoglycosides (eg, gentamicin), ethacrynic acid, or salicylates (eg, aspirin) because serious side effects to the kidneys (decreased ability to urinate) and ears (hearing loss) may occur
  • Chloral hydrate because side effects, such as excessive sweating, rapid heart beat, and changes in blood pressure, may occur
  • Digoxin or lithium because the risk of their side effects may be increased by Furosemide

This may not be a complete list of all interactions that may occur. Ask your health care provider if Furosemide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Furosemide :

Use Furosemide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Furosemide is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Furosemide at home, a health care provider will teach you how to use it. Be sure you understand how to use Furosemide. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Furosemide if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • Furosemide may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
  • If you miss a dose of Furosemide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Furosemide.

Important safety information:

  • Furosemide may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Furosemide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Furosemide may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Diabetes patients - Furosemide may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Blood pressure should be monitored when taking Furosemide.
  • Your doctor may also prescribe a potassium supplement while you use Furosemide. Check with your doctor before you use a salt substitute or other product that also has potassium in it.
  • Furosemide may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Furosemide. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Lab tests, including complete blood cell counts, may be performed while you use Furosemide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments..
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Furosemide while you are pregnant. Furosemide is found in breast milk. If you are or will be breast-feeding while you use Furosemide , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Furosemide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations; bladder spasm; blurred vision; constipation; cramping; dizziness; dizziness when rising from a seated or lying position; feeling of whirling motion; fever; headache; lightheadedness; mouth and stomach irritation; muscle spasm; nausea; redness; restlessness; seeing a yellow color; ringing in the ears; sensitivity to sunlight; vein inflammation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; diarrhea; drowsiness; dry mouth; excessive urination; hearing loss; loss of appetite; muscle pain/cramps/weakness; rapid or irregular heartbeat; restlessness; sudden joint pain; unusual bleeding or bruising; unusual thirst; unusual tiredness or weakness; vomiting; yellowing of the skin or eyes.

What is the shelf life of the pills?

  • The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
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